CBG vs. CBD: What's the Difference?
By now, most of us are pretty familiar with the trendiest new wellness ingredient on the block, cannabidiol, otherwise known as CBD. But cannabigerol (CBG) is another interesting cannabinoid derived from the cannabis plant. Most cannabis genetics only contain small amounts of CBG -- around one percent to be exact -- but its incredible potential is getting attention from health professionals
First Things First, What Exactly is CBG?
Cannabigerol (CBG) is a phytocannabinoid. Unlike endocannabinoids -- which are produced by the body -- phytocannabinoids are sourced from plants like cannabis. CBG is what's known as a non-intoxicating cannabinoid. Simply put, it doesn't get you high.
How Does CBG Work?
Plants are composed of many different chemical compounds. In the cannabis plant, these compounds include a group of chemicals called cannabinoids. Cannabinoids include CBD, THC, CBG, and over 120 other lesser-known chemicals that naturally occur in the cannabis plant.
CBG is difficult to extract from cannabis plants because it’s quickly converted into CBD and THC as cannabigerol acid (CBGA) is synthesized during plant growth. By the time a cannabis plant reaches adulthood, there’s only one percent or less CBG present in most strains. Some strains have been specially cultivated to include more CBG, but CBG is largely derived from younger cannabis plants that have not yet converted CBG into CBD and THC.
Like other cannabinoids (CBD, THC, etc.), though, CBG also works with your endocannabinoid system to imitate these compounds naturally.
Simply put, the endocannabinoid system is your built-in regulatory system that helps maintain equilibrium in your mind and body -- even when external factors and certain lifestyle choices throw it out of whack. You'll find endocannabinoids just about everywhere, from the immune system, central nervous system, and brain, to major organs, glands, connective tissues, and much more. This incredible system was only just discovered in the 90s and is considered essential to your body's ability to cultivate balanced health.
Okay, So What is CBD?
Arguably the MVP of the cannabinoid team -- CBD is everywhere these days. With the passage of the 2018 Farm Bill, hemp was officially legalized, finally bringing an end to decades of federal prohibition. Legalization also helped hemp-derived CBD soar into the mainstream, and today, you can find hemp-CBD products just about everywhere, from online to retail stores and everything in between.
Like its other beloved teammates, CBD works with the endocannabinoid system in many different ways, and related research is beginning to ramp up. CBD is showing promise for a wide variety of medical, wellness, and psychological uses.
What’s the Difference Between CBG and CBD?
Although both compounds are non-intoxicating cannabinoids found in the cannabis plant, CBG and CBD have a few notable differences. Here are some of them:
- Molecular Structure: CBG and CBD have different molecular structures, which simply refer to the number and arrangement of oxygen, carbon, and hydrogen atoms that constitute a cannabinoid. Dissimilar molecular structures mean that CBG and CBD have different three-dimensional shapes, and therefore bind with the body's cannabinoid receptors (CB1 and CB2) in different ways and act on the body distinctively. A cannabinoid's molecular structure also helps to determine the bioavailability (how well it's eventually absorbed and used by the body) of the cannabinoid as well as its degree of solubility in water.
- Pharmacology: CBG and CBD also activate your receptors differently. To give you a quick example, a 2011 study compared the effects of CBG and CBD at the 5-HT1A serotonin receptor, acting as an agonist or activator. CBG, on the other hand, behaves as an antagonist or blocker at the 5-HT1A receptor. The findings showed that a pre-treatment with CBG blocked CBD's anti-emetic effects, suggesting that the two cannabinoids bound to the same place -- but had opposing actions at this specific receptor. Pretty cool, right?
- Appetite Stimulation: Another interesting way in which CBG is different from CBD is in appetite stimulation. Research in rats showed that doses of CBG encouraged the tiny animals to eat more than double their normal food intake. Interestingly enough, in another study, CBG didn't induce any changes to feeding behavior but significantly reduced total food intake.
Should You Use CBG And CBD Together?
Many studies are showing that when you consume a single cannabinoid, it interacts positively with the body. However, there's an overwhelming amount of research suggesting that when more than one cannabinoid enters the bloodstream simultaneously, the benefits are exponentially multiplied. That benefit-boosting relationship is called the "Entourage Effect." The idea behind this incredible phenomenon is that a blend of cannabinoids works better than individually.
Here at Healist, we use the highest quality broad-spectrum hemp extract, which contains high levels of CBD, but includes other body-nourishing cannabinoids such as CBG, CBDA, CBN, and CBC, and therapeutic compounds like amino acids, terpenes, vitamins, and minerals that work in synergy with each other to provide you with positive wellness benefits.* And unlike full-spectrum hemp extract -- which contains around 0.3% THC -- our broad-spectrum hemp extracts are non-psychoactive with undetectable levels of THC. What's not to love?
Is CBG Used Similarly To CBD?
Yes! Just like CBD, the most common way CBG is produced for consumers is as an oil. You can get the body-nourishing benefits of CBG by using pure CBG oil. However, CBG oils can be difficult to find -- not to mention expensive.
The good news is that you can also get some of the benefits of CBD from using broad-spectrum CBD oils. Broad-spectrum CBD oils contain all the cannabinoids found in a cannabis plant, including CBD, but it doesn't include THC.
For the best broad-spectrum CBD oil on the planet, come on over to Healist, where you'll find Certificates of Analysis (COA) for every product to ensure you're getting exactly what you're looking for. What's more, we take the highest quality organically farmed CBD and blend it with active levels of botanicals backed by science to power your body's innate capacity to find calm, sleep, relief, and overall well-being -- just as nature intended.
What Are Some of the Potential Benefits of CBD?
The trials and studies exploring CBD and CBG's effects on humans are not yet conclusive. However, many preclinical reports and studies can provide insight. They help us to better understand some of the potential benefits of these popular cannabinoids, especially CBD. As we mentioned a little earlier, CBD won't give you an intoxicating feeling but may offer you other distinct therapeutic benefits such as:
Just about every popular cannabinoid helps to soothe feelings of tension and discomfort.*
We love the Relief Drops right here at Healist -- it’s a powerful blend of U.S. organically farmed CBD with active levels of organic ginger oil, turmeric oil, and a custom relief terpene blend to support your body's ability to soothe tired and sore muscles and general body discomfort.*
Supports Emotional Wellness
Each of the different cannabinoids plays a role in emotion support -- and CBD has shown immense promise to help ease feelings of stress and tension.* For those especially stressful days or anytime you're looking to find calm without the brain fog, the Calm Chews from Healist can help.*
These great-tasting on-the-go vegan gummies combine the highest quality U.S. organically farmed CBD with active levels of organic L-Theanine, Ashwagandha, and a custom calming terpene blend to support your body's ability to cope with daily stress as well as feelings of anxiety*.
Supports A Good Night’s Sleep
For those who struggle to achieve a good night's rest, using CBD can help.* This powerful cannabinoid can help to tackle barriers to sleep like tension and feelings of stress.* For a holistic approach, check out our Rest and Recovery Bundle -- a perfect pair of sleep support and muscle relief to help you feel recharged and ready to take on the day.*
There is still so much to discover about CBG, CBD, and the whole extended family of cannabinoids and other beneficial compounds that cannabis and hemp plants produce. Due to their relationship with the endocannabinoid system and the wide variety of incredible benefits that both CBG and CBD offer, we're sure to see these two cannabinoids becoming more and more mainstream in the years to come.
For the highest quality, U.S. grown organic CBD with clinically backed active natural ingredients that work with your body -- not against it -- head on over to Healist.
Whether you're looking for calm without the brain fog or relief from body discomfort, Healist has your back!*